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This patient demonstrated improvement in psychiatric symptoms with start and titration of tirzepatide and worsening in psychiatric symptoms with taper and discontinuation of tirzepatide (see Figure 1)

They have effectively retrained their metabolic preference

Chronic tiredness lasting more than two to three weeks warrants medical evaluation, even if youve made healthy lifestyle changes

How skinny shots miss the mark is that they focus on the psychological changes rather than the behavioral modification needed to sustain weight loss

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Bubble or Behavioral Reset